Lab-grown dairy: the next protein foray

Start-up companies are not going to produce milk in a lab – but the most valued components of it

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Lab-grown meat is getting a lot of attention along with plant-based meat substitutes. Dairy proteins may be the next product produced in a lab, for use in fluid “milk” production and processed dairy products like yogurt and cheese, to name a few.

What is synthetic dairy?

Perfect Day Inc., a California-based start-up, has recreated the proteins found in conventional cow’s milk without the use of animals. The company developed a form of genetically modified microflora that produces both whey and casein through a fermentation process.

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The approach can be loosely compared to the use of brewer’s yeast to produce alcohol. Yeast is used in controlled environments to create fermentation byproducts and the two processes simply employ different yeasts for a different purpose and output.

Perfect Day says their product is the exact same as the protein found in cow’s milk. Conventional milk is approximately 3.3 per cent protein, of which 82 per cent is casein and 18 per cent is whey. The other main elements are water, fat and carbohydrates.

Perfect Day has the technology to remake the small fraction of milk that is protein, arguably the most important component to produce other foods. The company suggests that its dairy protein is vegan and lactose-free, while providing the same high-quality nutrition as conventional dairy protein.

Milk produced by dairy cattle is a versatile ingredient used in various products worldwide. More than 70 per cent of milk sold from Canadian farms in 2019 is used for further processing, leaving the remainder to be consumed as fluid milk.

It may be difficult to produce full-fat milks that mimic the taste and texture of cow’s milk. Protein is just one component of fluid milk; milk fat is another, which would likely be the most difficult to mimic with plant-based alternatives. The structure of milk fat provides a specific taste and mouth feel when drinking milk, and this may be a tougher formulation challenge than creating proteins to be used in cheese or yogurt.

Perfect Day has partnered with food production powerhouse Archer Daniels Midland (ADM), among others, to move towards full-scale production.

Products such as yogurt and cheese may be more suitable for using lab-grown casein and whey compared to fluid milk or butter. The synthetic proteins could be used to replace dairy milk ingredients or to complement them.

In yogurt production, for example, protein is often added to improve texture. There are differing proportions of milk components in various processed products. This means that fermented casein and whey proteins could augment or replace conventional protein ingredients.

Butter, for example, is made from milk fat and has almost no protein. We’ve long had a plant-based alternative to butter — margarine.

The Canadian per capita consumption of butter increased from 2.72 kilograms to 3.21 kilograms from 2007 to 2016. This increase in butter demand has led to an excess of milk protein in the marketplace in both Canada and the United States.

That said, the potential use of animal-free dairy protein goes far beyond traditional dairy products. Hot dogs that contain milk powder and granola bars that contain modified milk ingredients are examples of the many foods that could use this alternative dairy protein.

Tackling malnutrition?

Perfect Day CEO Ryan Pandya said last year: “We began to look into how we can use our protein to prevent stunted growth and malnutrition in the developing world.” This suggests Perfect Day’s focus is on providing ingredients rather than producing milk.

While it remains to be seen if these fermented proteins can be produced economically, their introduction into the marketplace could cause significant disruption to the dairy industry.

There would be additional disruption because of the change in relative demand for protein and other milk components. We would likely end up with more significant surpluses of proteins from both conventional dairy and synthetic production.

The future

Many issues need to be resolved before these products arrive in our supermarkets. The economics of production have to work. Products need to be reformulated to incorporate the fermented proteins with other ingredients to replace the milk components.

The Canadian Food Inspection Agency currently describes milk as being produced by an animal. Milk in Canada is also subject to a supply management system that includes quota for production.

Will synthetic casein and whey be subject to the same system? The regulatory environment will require significant clarification, and any changes will be vigorously debated by various interests.

Some consumers will highly value the fact that animals are not required to produce these proteins, creating a vegan, lactose-free product. There will also be a perception that synthetic dairy proteins will have a smaller environmental footprint.

Other consumers will likely have concerns that the proteins are produced using a genetically modified yeast.

Despite these uncertainties, we will likely see synthetic dairy products on grocery shelves within a few years.

Mitchell Gingerich is a graduate research assistant in the Department of Food, Agriculture and Resource Economics, University of Guelph. Michael von Massow is an associate professor, Food Economics, University of Guelph.

This first appeared in The Conversation:

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